Selina Parry PT et al

Purpose

The purpose was to determine (a) safety and feasibility of functional electrical stimulation (FES)-RT300 Supine and (b) compare RT300 Supine FES to case-matched controls in terms of functional recovery and delirium outcomes.

Materials and methods

Sixteen adult intensive care unit patients with sepsis ventilated for more than 48 hours and in the intensive care unit for at least 4 days were included. Eight subjects underwent RT300 Supine FES in addition to usual care and were compared to 8 case-matched control individuals. Primary outcomes were safety and feasibility of RT300 Supine FES. Secondary outcomes were Physical Function in Intensive Care Test scored on awakening, time to reach functional milestones, and incidence and duration of delirium.

Results

One minor adverse event was recorded. Sixty-nine out of total possible 95 FES sessions (73%) were completed. A visible or palpable contraction was present 80% of the time. There was an improvement in Physical Function in Intensive Care Test score of 3.9/10 points in the intervention cohort with faster recovery of functional milestones. There was also a shorter duration of delirium in the intervention cohort.

Conclusions

The delivery of RT300 Supine FES is both safe and feasible. The preliminary findings suggest that RT300 Supine FES may improve function and reduce delirium. Further research is required to confirm the findings of this study and evaluate the efficacy of RT300 Supine FES.

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